FAM66B
Chr 8family with sequence similarity 66 member B
Also known as: FAM66E
Clinical Summary— FAM66B
📋
ClinVar Variants
37 Pathogenic / Likely Pathogenic of 107 total submissions
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
107 submitted variants in ClinVar
Classification Summary
Pathogenic37
Likely Benign6
Benign64
37
Pathogenic
6
Likely Benign
64
Benign
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | — | — | — | — | 37 |
Likely Pathogenic | — | — | — | — | 0 |
VUS | — | — | — | — | 0 |
Likely Benign | — | — | — | — | 6 |
Benign | — | — | — | — | 64 |
| Total | — | 107 | |||
Counts from ClinVar esearch · Updated hourly
View in ClinVar →FAM66B · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →Clinical Literature
Landmark / reviewRecent case evidence
Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
Copy Number Variants Captured by the Array Comparative Genomic Hybridization in a Cohort of Patients Affected with Hereditary Colorectal Cancer in Sri Lanka: The First CNV Analysis Study of the Hereditary Colorectal Cancer in the Sri Lankan Population
Wijesiriwardhana P et al.·Asian Pac J Cancer Prev
2021Cohort
Current knowledge on the role of extracellular vesicles in endometrial receptivity
Sui C et al.·Eur J Med Res
2023
Pet ownership in pregnancy and methylation pattern in cord blood
Danielewicz H et al.·Genes Immun
2021
Integrative genome-wide analyses reveal the transcriptional aberrations in Japanese esophageal squamous cell carcinoma
Takemoto A et al.·Cancer Sci
2021
Pan-glioma analyses reveal species- and tumor-specific regulation of neuron-glioma synapse genes by lncRNAs
Xiong W et al.·Front Genet
2023
Top 5 full-text resultsSearch PubTator3 ↗
Key Publications
Landmark & review papers · by relevance
Deregulated Long Non-Coding RNAs (lncRNA) as Promising Biomarkers in Hidradenitis Suppurativa.
Radhakrishna U et al.·J Clin Med
2024
Top 1 results · since 2015Search PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
No open access results found
Top 5 resultsSearch Europe PMC ↗
External Resources
Links to major genomics databases and tools