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EIG17
Chr 19ADhyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
Also known as: BCNG-2, BCNG2, EIG17, FEB2, GEFSP11, HAC-1
The protein is a hyperpolarization-activated cation channel that generates pacemaker activity in the heart and brain and is activated by cAMP to produce fast, large currents. Mutations cause generalized epilepsy with febrile seizures plus type 11 and familial febrile seizures, with inheritance following an autosomal dominant pattern. The epilepsy phenotypes typically involve febrile seizures that may progress to other generalized seizure types.
Some data sources returned errors (2)
ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/EIG17?content-type=application/json&expand=1
gnomad: Error: Gene not found
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
EIG17 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
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External Resources
Links to major genomics databases and tools