EIF1AY
Chr Yeukaryotic translation initiation factor 1A Y-linked
Also known as: eIF-4C
The protein is a component of the ribosomal translation initiation machinery that facilitates mRNA scanning, start codon recognition, and assembly of the 80S ribosome complex for protein synthesis. This gene is located on the Y chromosome and follows Y-linked inheritance, passing from father to son. Currently, no specific diseases have been definitively associated with mutations in this gene.
Population Genetics & Constraint
gnomAD v4 — loss-of-function & missense intolerance
Highly tolerant — LoF variants common in population
Mild missense constraint
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
EIF1AY · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →External Resources
Links to major genomics databases and tools