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DYT9

Chr 1AD

solute carrier family 2 member 1

Also known as: CSE, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT-1, GLUT1

This gene encodes a major glucose transporter in the blood-brain barrier that is located primarily in cell membranes and on cell surfaces. Mutations cause dystonia 9, characterized by paroxysmal exertion-induced dyskinesia with autosomal dominant inheritance. The dystonic episodes are specifically triggered by physical exertion.

OMIMResearchSummary from RefSeq, OMIM
LOFmechanismAD1 OMIM phenotype
Clinical SummaryDYT9
💊
Clinical Trials
1 active or recruiting trial — potential therapeutic options may be available
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/DYT9?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

DYT9 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold
Clinical Literature
Open Research Assistant →
Key Publications
Landmark & review papers · by relevance
PubMed
Top 1 results · since 2015Search PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC