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DYT15

Chr 18AD

dystonia 15, myoclonic

The protein encoded by DYT15 functions in cellular processes that affect movement control. Mutations cause dystonia-15, a myoclonic dystonia characterized by rapid, jerky muscle contractions combined with sustained muscle contractions that cause twisting movements. The condition follows autosomal dominant inheritance.

OMIMResearchSummary from OMIM
AD1 OMIM phenotype
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/DYT15?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

DYT15 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

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Clinical Literature
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Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
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Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC