DRC11L

Chr 7

dynein regulatory complex subunit 11 like

Also known as: IQCA1L, IQCA1P1

Predicted to enable ATP hydrolysis activity and microtubule severing ATPase activity. Predicted to be involved in microtubule cytoskeleton organization. [provided by Alliance of Genome Resources, Jul 2025]

29
ClinVar variants
28
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryDRC11L
📋
ClinVar Variants
28 Pathogenic / Likely Pathogenic of 29 total submissions
Some data sources returned errors (3)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/DRC11L?content-type=application/json&expand=1

gnomad: Error: Gene not found

omim: Error: OMIM fetch failed: 429

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

29 submitted variants in ClinVar

Classification Summary

Pathogenic25
Likely Pathogenic3
Likely Benign1
25
Pathogenic
3
Likely Pathogenic
1
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
25
Likely Pathogenic
3
VUS
0
Likely Benign
1
Benign
0
Total29

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

DRC11L · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.