DNAAF11
Chr 8ARdynein axonemal assembly factor 11
Also known as: CILD19, LRRC6, LRTP, TSLRP, tilB
The protein encoded by this gene contains several leucine-rich repeat domains and appears to be involved in the motility of cilia. Defects in this gene are a cause of primary ciliary dyskinesia-19 (CILD19). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4, 11 and 22. [provided by RefSeq, Apr 2016]
Primary Disease Associations & Inheritance
Clinical highlights
Population Genetics & Constraint
gnomAD v4 — loss-of-function & missense intolerance
Highly tolerant — LoF variants common in population
Tolerant to missense variation
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
DNAAF11 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
Cystinosis and Mitochondrial Metabolism
RECRUITINGEvolution of Metabolic and Immune Dysfunction in In-transit Melanoma
RECRUITINGClinical Research on Acute Intermittent Porphyria and the Use of Carbohydrate-Rich Diet as a Treatment
RECRUITINGFemale Fertility, Environmental Agents and Stress Oxidant
RECRUITINGEffects of Gender-Affirming Hormone Therapy on Cardiovascular, Metabolic, and Mental Health Outcomes in Transgender Adults.
NOT YET RECRUITINGTocotrienol Supplementa as A Senolytic Agent in Middle-aged Adults
RECRUITING" Development of Primary Cultures of Diaphragmatic Myoblasts for Basic Research Purposes "
NOT YET RECRUITINGEvaluating the Impact of GLP-1 Receptor Agonists With Total Neoadjuvant Therapy in Rectal Cancer
NOT YET RECRUITINGVITAL: Vaccination, Immunity, Time-restricted Eating, Aging and Lifestyle
RECRUITINGExternal Resources
Links to major genomics databases and tools