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CZ1P-ASNS

Chr 7

CZ1P-ASNS readthrough

NCBI Gene: 107986827

This locus represents a readthrough transcript between the CCZ1P pseudogene and ASNS gene that is predicted to undergo nonsense-mediated decay and is unlikely to produce a functional protein product. No disease associations have been established for this readthrough transcript, as it does not appear to generate a stable protein. Clinical significance remains unclear given the lack of protein production from this transcriptional unit.

ResearchSummary from RefSeq

This locus represents naturally occurring readthrough transcription between the neighboring CCZ1P (CCZ1 homolog, vacuolar protein trafficking and biogenesis associated pseudogene) and ASNS (asparagine synthetase) genes on chromosome 7. The readthrough transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Jun 2017]

ResearchGenerating clinical summary…

Active trials

Pubs (1 yr)

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P/LP submissions

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P/LP missense

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LOEUF

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Mechanism

Some data sources returned errors (3)