CTAGE15

Chr 7

CTAGE family member 15

Also known as: CTAGE15P, cTAGE-15

NCBI Gene: 441294ENSG00000271079UniProt: A4D2H0

Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; protein secretion; and vesicle cargo loading. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum exit site and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jul 2025]

101
ClinVar variants
47
Pathogenic / LP
—
pLI score
0
Active trials
Clinical Summary— CTAGE15
📋
ClinVar Variants
47 Pathogenic / Likely Pathogenic· 48 VUS of 101 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

101 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic46
Likely Pathogenic1
VUS48
Likely Benign6
46
Pathogenic
1
Likely Pathogenic
48
VUS
6
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
0
0
46
0
46
Likely Pathogenic
0
0
1
0
1
VUS
0
43
5
0
48
Likely Benign
0
4
2
0
6
Benign
0
0
0
0
0
Total047540101

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

CTAGE15 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

OMIM

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence

No publications found for CTAGE15

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools