CSN3
Chr 4casein kappa
Some data sources returned errors (1)
ncbi: Error: NCBI fetch failed: 429 https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi
Population Genetics & Constraint
gnomAD v4 — loss-of-function & missense intolerance
Tolerant — LoF & missense variants common in population
LoF Constraint?
1.71LOEUF
pLI 0.012
Z-score 0.48
OE 0.74 (0.33–1.71)
Highly tolerant — LoF variants common in population
Missense Constraint?
-0.03Z-score
OE missense 1.01 (0.86–1.19)
105 obs / 104.2 exp
Tolerant to missense variation
Observed / Expected Ratios?
LoF OE?0.74 (0.33–1.71)
0≤0.351.4
Missense OE?1.01 (0.86–1.19)
0≤0.61.4
Synonymous OE?1.18
0≤1.21.6
LoF obs/exp: 3 / 4.0Missense obs/exp: 105 / 104.2Syn Z: -0.86
ClinVar
No ClinVar data available.
Protein Context — Lollipop Plot
CSN3 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →External Resources
Links to major genomics databases and tools