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CILD47

Chr 1AR

tumor protein p73

Also known as: CILD47, P73

This gene encodes a member of the p53 family of transcription factors that regulates cellular stress responses and development. Mutations cause autosomal recessive primary ciliary dyskinesia type 47 and lissencephaly, affecting both respiratory cilia function and brain development. The combination of ciliary dysfunction and cortical malformation represents a rare phenotype involving both pulmonary and central nervous systems.

OMIMResearchSummary from RefSeq, OMIM
AR1 OMIM phenotype
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/CILD47?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

CILD47 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

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Clinical Literature
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No publications found for CILD47