CHUK-DT

Chr 10

CHUK divergent transcript

I cannot provide a clinical gene summary for CHUK-DT because no functional, phenotypic, or inheritance information was provided in the data. CHUK-DT appears to be a non-coding transcript associated with the CHUK gene region, but without additional information about its role in disease or protein function, I cannot generate the requested clinical summary.

Research

ResearchGenerating clinical summary…

Clinical Summary— CHUK-DT

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ClinVar Variants

8 VUS of 19 total submissions

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Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

19 submitted variants in ClinVar

ClinVar

Classification Summary

VUS8

Likely Benign1

Benign5

VUS

Likely Benign

Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

Classification	LoF	Missense + Inframe	Non-coding	Total
Pathogenic	0	0	0	0
Likely Pathogenic	0	0	0	0
VUS	1	7	0	8
Likely Benign	0	1	0	1
Benign	0	3	2	5
Total	1	11	2	14

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

3 pathogenic / likely-pathogenic (of 5) ClinVar copy-number / structural variants overlap CHUK-DT — these span large chromosomal regions, not the gene specifically, and are excluded from the counts above. Explore in CNV tools →