CFAP263

Chr 16

cilia and flagella associated protein 263

Also known as: CCDC113, HSPC065

Involved in cilium assembly. Located in centriolar satellite and ciliary basal body. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025]

0
Active trials
21
Pathogenic / LP
128
ClinVar variants
1
Pubs (1 yr)
Missense Z
LOEUF
Clinical SummaryCFAP263
📋
ClinVar Variants
21 Pathogenic / Likely Pathogenic· 102 VUS of 128 total submissions
Some data sources returned errors (1)

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

128 submitted variants in ClinVar

Classification Summary

Pathogenic18
Likely Pathogenic3
VUS102
Likely Benign5
18
Pathogenic
3
Likely Pathogenic
102
VUS
5
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
0
0
18
0
18
Likely Pathogenic
0
0
3
0
3
VUS
0
95
7
0
102
Likely Benign
0
4
0
1
5
Benign
0
0
0
0
0
Total099281128

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

CFAP263 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Landmark / reviewRecent case evidence
Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
PubTator3
Top 1 full-text resultsSearch PubTator3 ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found