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CAVIPMR

Chr 1

ER membrane protein complex subunit 1

Also known as: CAVIPMR, KIAA0090

The protein is a subunit of the endoplasmic reticulum membrane protein complex (EMC), which facilitates membrane protein insertion and folding. Autosomal recessive mutations cause cerebellar atrophy, visual impairment, and psychomotor retardation. This condition affects the central nervous system and visual system, presenting with developmental delays and progressive cerebellar degeneration.

ResearchSummary from RefSeq, OMIM
Some data sources returned errors (3)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/CAVIPMR?content-type=application/json&expand=1

gnomad: Error: Gene not found

omim: Error: OMIM fetch failed: 429

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

CAVIPMR · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
PubTator3
Top 2 full-text resultsSearch PubTator3 ↗
Key Publications
Landmark & review papers · by relevance
PubMed
Top 1 results · since 2015Search PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found