C1QTNF7
Chr 4C1q and TNF related 7
Also known as: CTRP7, ZACRP7
Predicted to enable identical protein binding activity. Predicted to be located in endoplasmic reticulum lumen and obsolete extracellular space. [provided by Alliance of Genome Resources, Jun 2026]
ResearchGenerating clinical summary…
Population Genetics & Constraint
gnomAD v4 — loss-of-function & missense intolerance
Tolerant — LoF & missense variants common in population
LoF Constraint?
1.45LOEUF
pLI 0.000
Z-score 0.62
OE 0.78 (0.44–1.45)
Highly tolerant — LoF variants common in population
Missense Constraint?
0.73Z-score
OE missense 0.84 (0.73–0.97)
142 obs / 168.7 exp
Mild missense constraint
Observed / Expected Ratios?
LoF OE?0.78 (0.44–1.45)
0≤0.351.4
Missense OE?0.84 (0.73–0.97)
0≤0.61.4
Synonymous OE?0.86
0≤1.21.6
LoF obs/exp: 7 / 9.0Missense obs/exp: 142 / 168.7Syn Z: 0.90
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
C1QTNF7 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →External Resources
Links to major genomics databases and tools