BANF2
Chr 20BANF family member 2
Also known as: BAF-L, BAF2, BAFL, C20orf179
BANF2 encodes a nuclear protein that enables identical protein binding and is predicted to be involved in chromosome organization, with potential roles in regulating BANF1 function in a tissue-specific manner. The gene shows low constraint against loss-of-function variants (pLI 0.01, LOEUF 1.63), and currently no human disease associations have been established for pathogenic variants in this gene. Further research is needed to determine whether BANF2 mutations cause pediatric neurological disorders.
Population Genetics & Constraint
gnomAD v4 — loss-of-function & missense intolerance
Highly tolerant — LoF variants common in population
Mild missense constraint
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
BANF2 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →External Resources
Links to major genomics databases and tools