ASAP1-IT1

Chr 8

ASAP1 intronic transcript 1

Also known as: ASAP1-IT, ASAP1IT, ASAP1IT1, DDEF1IT1, HSPC054, NCRNA00050

I cannot provide a clinical summary for ASAP1-IT1 as no information about this gene's protein function, associated diseases, or inheritance pattern was provided in the data below the instructions. To write an accurate clinical summary, I would need specific information about what protein this gene encodes, what neurological conditions result from mutations, and the inheritance pattern observed in affected families.

0
Active trials
2
Pubs (1 yr)
55
P/LP submissions
P/LP missense
LOEUF
Mechanism
Clinical SummaryASAP1-IT1
📋
ClinVar Variants
55 unique Pathogenic / Likely Pathogenic· 7 VUS of 62 total submissions
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/ASAP1-IT1?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

62 submitted variants in ClinVar

Classification Summary

Pathogenic54
Likely Pathogenic1
VUS7
54
Pathogenic
1
Likely Pathogenic
7
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
54
Likely Pathogenic
1
VUS
7
Likely Benign
0
Benign
0
Total62

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

ASAP1-IT1 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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