ARMCX5-GPRASP2
Chr XARMCX5-GPRASP2 readthrough
Also known as: ARMCX5-GPRASP2-BHLHB9-LINC00630
This locus represents a complex readthrough transcription region on chromosome X that may produce proteins identical to GPRASP2 or BHLHB9, where GPRASP2 functions in G protein-coupled receptor trafficking and sorting. The clinical significance of variants in this readthrough transcript region remains unclear, as specific disease associations have not been established. Any potential inheritance would follow an X-linked pattern.
Some data sources returned errors (1)
gnomad: Error: Gene not found
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
500 submitted variants in ClinVar
Classification Summary
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | 0 | 1 | 90 | 0 | 91 |
Likely Pathogenic | 0 | 1 | 1 | 0 | 2 |
VUS | 1 | 295 | 6 | 0 | 302 |
Likely Benign | 0 | 25 | 1 | 16 | 42 |
Benign | 0 | 5 | 5 | 3 | 13 |
Conflicting | — | 4 | |||
| Total | 1 | 327 | 103 | 19 | 454 |
LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
ARMCX5-GPRASP2 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools