AIM2
Chr 1absent in melanoma 2
Also known as: PYHIN4
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008]
Some data sources returned errors (1)
omim: Error: OMIM fetch failed: 429
Population Genetics & Constraint
gnomAD v4 — loss-of-function & missense intolerance
Highly tolerant — LoF variants common in population
Mild missense constraint
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
AIM2 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
Prediction of Germline BRCA 1/2 Genes From Healthy Ovaries
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ACTIVE NOT RECRUITINGA Nutrition & Exercise Prehabilitation Intervention on Inflammatory Biomarkers in AI Cancer Patients
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ACTIVE NOT RECRUITINGProtective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Associated Cardiac Dysfunction
RECRUITINGFamilial Inflammatory Bowel Disease Early Risk
RECRUITINGSimultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma
ACTIVE NOT RECRUITINGNorthwestern Neuromuscular Disease Biorepository
RECRUITINGDoes Repeat Influenza Vaccination Constrain Influenza Immune Responses and Protection
ACTIVE NOT RECRUITINGExternal Resources
Links to major genomics databases and tools