AGS9

Chr 12AR

RNA, U7 small nuclear 1

Also known as: AGS9, RNU7, U7.1

The AGS9 protein is implicated in Aicardi-Goutieres syndrome, a severe early-onset neuroinflammatory disorder characterized by progressive encephalopathy, calcifications of the basal ganglia, and chronic cerebrospinal fluid lymphocytosis. Mutations cause Aicardi-Goutieres syndrome 9 with autosomal recessive inheritance.

Summary from RefSeq, OMIM
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Primary Disease Associations & Inheritance

Aicardi-Goutieres syndrome 9MIM #619487
AR
0
Active trials
0
Pubs (1 yr)
0
P/LP submissions
P/LP missense
LOEUF
Mechanism
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/AGS9?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

AGS9 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found