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GAGE2D
Chr XG antigen 2D
Also known as: CT4.8, GAGE-2D, GAGE-8, GAGE8
The GAGE2D protein is a member of the GAGE (G antigen) family, which are normally expressed in germ cells and some cancers but have limited known function in typical somatic tissues. Currently, no definitive disease associations have been established for GAGE2D mutations in pediatric or adult populations. The gene shows relatively low constraint against loss-of-function variants, suggesting that complete loss may be tolerated.
Some data sources returned errors (1)
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Population Genetics & Constraint
gnomAD v4 — loss-of-function & missense intolerance
Highly tolerant — LoF variants common in population
Mild missense constraint
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
GAGE2D · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools